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Best Defense for Week 12 Fantasy Football (2024)

Best Defense for Week 12 Fantasy Football (2024)

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As we head into Week 12 of the 2024 fantasy football season, choosing the best defense can make or break your matchups. With the fantasy playoffs just around the corner, every point counts, and finding the perfect defensive unit can give you the edge you need. Today, we break down the top DSTS for Week 12 fantasy football. Whether you’re streaming DSTs based on matchups or sticking with a tried-and-true option, making the right call is crucial.

In this article, we’ll break down the best defensive plays for Week 12, highlighting top choices, sleeper options, and matchups to exploit to help you dominate your league. Let’s dive into the stats, trends, and key factors to consider for this week’s best DSTs.

Top Defenses to Start in Week 12 Fantasy Football

Washington Commanders vs. Dallas Cowboys

As of Tuesday morning, this Washington Commanders DST is rostered in 29% of leagues on Sleeper. Last week, they gave up 26 points in an 18-26 loss to Jalen Hurts and the Philadelphia Eagles. This week, they get a home game against Cooper Rush and the struggling Dallas Cowboys. They should control the ball and end up being one of the best defense pickups off the waiver wire for Week 12.

Rookie sensation Jayden Daniels and this offense have looked great this year. Terry McLaurin, Brian Robinson, Austin Ekeler, and Zach Ertz have all exceeded expectations. As a result, they should control the ball and ultimately, this game. Recently, the Commanders acquired CB Marshon Lattimore via trade with the Saints. Look for the Commanders to take advantage of this matchup and be one of the best defense pickups this week for fantasy football.

Tampa Bay Buccaneers @ New York Giants

Coming off a bye week, the Tampa Bay Buccaneers will go on the road to take on the New York Giants. Daniel Jones has been benched and Tommy DeVito will take over as the starter. Rostered in just 23% of leagues on Sleeper, this DST could be solid for a stretch of upcoming games. Their next few opponents are the Giants, Panthers (twice), Raiders, Chargers, and the Cowboys. Don’t be afraid to pick them up and stream them for a few weeks or into the fantasy football playoffs.

Arizona Cardinals @ Seattle Seahawks

Finally, the Arizona Cardinals are one of the best defense pickups for Week 12 of the fantasy football season. This week, they take on Geno Smith and the Seahawks in Seattle. Fresh off a bye week, the Cardinals are in the hunt for a division title at this point. According to our free fantasy football tools, the Seahawks give up the fifth-most points to opposing DSTs. Additionally, the Seahawks are 32nd in rush EPA since Week 7.

Watch our Lead Fantasy Football Analyst Pete Nova, break down the best defense for Week 12 fantasy football below.


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